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An Overview of CellML 1.1, a Biological Model Description Language

The Bioengineering Institute, University of Auckland, Private Bag 92019 Auckland, New Zealand, a.cuellar{at}auckland.ac.nz

Catherine M. Lloyd

The Bioengineering Institute, University of Auckland, Private Bag 92019 Auckland, New Zealand

Poul F. Nielsen

The Bioengineering Institute, University of Auckland, Private Bag 92019 Auckland, New Zealand

David P. Bullivant

The Bioengineering Institute, University of Auckland, Private Bag 92019 Auckland, New Zealand

David P. Nickerson

The Bioengineering Institute, University of Auckland, Private Bag 92019 Auckland, New Zealand

Peter J. Hunter

The Bioengineering Institute, University of Auckland, Private Bag 92019 Auckland, New Zealand

CellML is an XML-based exchange format developed by the University of Auckland in collaboration with Physiome Sciences, Inc. CellML 1.1 has a component-based architecture allowing a modeller to build complex systems of models that expand and reuse previously published models. CellML Metadata is a format for encoding contextual information for a model. CellML 1.1 can be used in conjunction with CellML Metadata to provide a complete description of the structure and underlying mathematics of biological models. A repository of over 200 electrophysiological, mechanical, signal transduction, and metabolic pathway models is available at www.cellml.org.

Key Words: Biological model • XML • markup language • mathematical model

SIMULATION, Vol. 79, No. 12, 740-747 (2003)
DOI: 10.1177/0037549703040939


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